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Similar to the Global Positioning Systems used in vehicles today to help us reach our intended
destinations, our pharmacogenetic products enable a 'genetic prescription system' to be implemented from
correlations of gene variation and drug response outcomes. This drug GPS will lead physicians and patients to
their desired treatment goal, resulting in more effective healthcare.
The initial target markets for our products are the management of psychiatric, cardiovascular, and diabetes
medications. The Genomas mission is to be the leading company in DNA-guided medicine by developing a new standard
of care using proprietary drug management systems guided by the patient's own genome. Our products, PhyzioType
Systems, give physicians the ability to personalize clinical management by selecting the drug with the least
risk and greatest efficacy.
The company has pursued the Drug GPS model through a pipeline of PhyzioType products.
The HILOmet PhyzioType System is in the clinical market for DNA-Guided prescription of antidepressants
and stimulants. A next generation of PhyzioType products are nearing beta launch for DNA-Guided prescription
of antipsychotics (PIMS) and statins (SINM), and under development for anti-diabetic drugs (GLIM).
Based on our experience with clinical practice and patient referrals, we believe that our products
can be readily integrated with medical practice and prescribing protocols. Our products improve medical management
and boost patient compliance with pharmacotherapy. The critical junctures for utilization of our products are
during follow up of patients already experiencing drug resistance or intolerance to assist the physician in
determining the cause of poor response or side effects, and upon initiation of drug therapy in high-risk or
vulnerable patients.
For patients identified by the clinician as high-risk or vulnerable, prognostic use of our products has
substantial clinical value and cost benefit. These patients have existing co-morbidities such as
severe depression or diabetes and are vulnerable to dire consequences (e.g. suicide or myocardial
infarcts). Physicians may adopt our PhyzioType tests at the initial point of prescription to mitigate the
risks inherent in trial and error prescribing. Prognostic use may be clinically beneficial for young
patients 8 to 18 years old, a sector of the population increasingly being prescribed psychotropic
drugs.
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